Early Onset Adult Deafness (Rhodesian Ridgeback)

Early Onset Adult Deafness (Rhodesian Ridgeback)

¥16,600
  • TEST OVERVIEW:
    An early onset adult deafness which results in the progressing hearing loss in the breed. Deafness is usually seen at around 2 years of age. Confirmation of deafness is usually confirmed via BAER test.
  • カテゴリー:
    神経系・神経疾患 - 脳や脊髄、神経に関連する疾患
  • static-content..gene:
    EPS8L2
  • Variant Detected:
    chr18:26126095-26126107: 13 bp deletion (del GTGCACTTCCTCT)
  • Severity:
    Moderate. This disease can cause significant signs of discomfort and/or dysfunction in affected animals. It may involve relatively high treatment/management costs, and can sometimes reduce life expectancy.
  • MODE OF INHERITANCE:
    Autosomal Recessive
  • RESEARCH CITATION(S):
    awakami T, Raghavan V, Ruhe AL, Jensen MK, Milano A, Nelson TC, Boyko AR. Early onset adult deafness in the Rhodesian Ridgeback dog is associated with an in-frame deletion in the EPS8L2 gene. PLoS One. 2022 Apr 6;17(4):e0264365. [PubMed: 35385474] Strain GM. The Genetics of Deafness in Domestic Animals. Front Vet Sci. 2015 Sep 8;2:29. doi: 10.3389/fvets.2015.00029. [PubMed: 26664958]

Early Onset Adult Deafness (Rhodesian Ridgeback)

¥16,600

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